Expert list · Last reviewed April 17, 2026
Best Hematologists for Lymphoma in South Dakota
Find top hematologists in South Dakota who treat lymphoma, with details on clinical focus, affiliations, and published research.
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South Dakota has a small but capable bench of hematologists who treat lymphoma, spread across Sioux Falls, Watertown, and Rapid City — here is where to start your search.
If you or someone you love has been told the lymph nodes on a scan look suspicious, or a biopsy came back as Hodgkin or non-Hodgkin lymphoma, the next step is finding a blood cancer specialist who sees these cases regularly. The six hematologists below practice across the state, work with major regional cancer programs like Avera, Sanford, and Monument Health, and have published peer-reviewed research that signals ongoing academic engagement.
Dr. Miroslaw Mazurczak practices hematology and oncology in Sioux Falls and sees patients through Osceola Community Hospital, Orange City Area Health System, and Sanford Sheldon Medical Center. His clinical work spans blood cancers and solid tumors, and he has been part of multicenter trials through the Eastern Cooperative Oncology Group. One 2018 study in JCO Precision Oncology 4 describes how his community cancer program used a video-conferenced molecular tumor board to bring gene-sequencing-guided treatment to patients who would otherwise have to travel. For lymphoma patients, that infrastructure matters when tumor genetics might open the door to a targeted drug or trial.
Dr. Bipinkumar Amin is based in Watertown, where he treats patients at Prairie Lakes Hospital and works with Chippewa County Hospital and Sanford Children's Hospital. He is one of the few hematology options in the northeastern corner of the state, which matters for patients who want to stay close to home during months of infusion therapy. He has contributed to peer-reviewed evidence syntheses, including a 2025 systematic review comparing anesthesia approaches for upper-limb surgery 6 — a reminder that lymphoma care often means coordinating with surgeons for biopsies, port placement, and supportive procedures.
Dr. James Kuzman is a hematologist at Monument Health Rapid City Hospital, making him the primary West River option in the specialty. He also sees patients at Monument Health Orthopedic and Specialty Hospital and Hans P Peterson Memorial Hospital. Before his clinical career he published research on how thyroid hormone shapes heart muscle, including a 2005 paper in Circulation 7 and follow-up work in Endocrinology 9. That background is useful context for a lymphoma specialist: several chemotherapy regimens, especially those containing doxorubicin, put stress on the heart, and a doctor who thinks about cardiac biology is one who will watch your heart closely during treatment.
Dr. Benjamin Solomon practices in Sioux Falls with admitting privileges at Lakes Regional Healthcare, Avera Holy Family Hospital, and Pipestone County Medical Center. He led a WIN Consortium phase I trial 14 that paired an immune checkpoint inhibitor with two targeted drugs in advanced lung cancer, and he has contributed to work on biomarker-guided therapy selection 16. That experience reading early-phase trial results is directly useful if your lymphoma has been hard to treat and your team is weighing a clinical trial or a newer antibody-drug conjugate.
Dr. Vinod Parameswaran treats patients in Sioux Falls at Avera McKennan Hospital and University Health Center and Floyd County Medical Center. His publications include a 2024 case report on persistent relapsing babesiosis in a patient whose B-cell lymphoma treatment with rituximab had wiped out the antibody response needed to clear the parasite 18. That is not a side story for lymphoma patients — most modern regimens involve antibody-based drugs that leave you vulnerable to unusual infections, and having a doctor who has published on how to recognize and manage them is a real advantage.
Dr. Mark Huber is another Sioux Falls hematologist with privileges at Lakes Regional Healthcare, Osceola Community Hospital, and UnityPoint Health St. Luke's in Sioux City. He first-authored a review in Annals of Hematology 21 on treating immune thrombocytopenic purpura, a low-platelet condition that sometimes shows up alongside or after lymphoma, and a PubMed case report on systemic mastocytosis that looked like metastatic breast cancer on imaging 23. The common thread is a doctor used to thinking carefully when the diagnosis does not line up cleanly.
What to look for in a hematologist for lymphoma
- Board certification in hematology or hematology and medical oncology
- Academic affiliation with a teaching hospital or cancer center
- Experience with your specific lymphoma subtype, not just "lymphoma" in general
- Access to clinical trials and molecular testing through their cancer program
- Wait time and whether they are accepting new patients
- Insurance and hospital network compatibility
Questions to ask before your first appointment
- How many patients with my type of lymphoma do you treat each year?
- Will my case be reviewed at a tumor board or with a pathology second opinion?
- What clinical trials are open at your center for my subtype?
- Who on your team handles infusion scheduling and side-effect calls after hours?
- How do you monitor heart and lung function during treatment?
- If I need stem cell transplant or CAR-T therapy, where do you refer?
The bottom line
Lymphoma care in South Dakota is concentrated in Sioux Falls, with outposts in Watertown and Rapid City, so your geography will narrow the list quickly. Start with the specialist closest to you, bring a list of your symptoms and recent imaging, and ask directly about trial access and transplant referral pathways. If your subtype is rare or your first-line treatment has failed, it is reasonable to ask for a second opinion at a comprehensive cancer center while continuing local care.
Sources
- 1.A phase II trial of Triapine® (NSC# 663249) and gemcitabine as second line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503 — Investigational New Drugs, 2009. DOI
- 2.Phase II study of dichloroacetate, an inhibitor of pyruvate dehydrogenase, in combination with chemoradiotherapy for unresected, locally advanced head and neck squamous cell carcinoma — Investigational New Drugs, 2022. DOI
- 3.Verrucous Carcinoma of the Esophagus: A Potential Diagnostic Dilemma — Case Reports in Gastroenterology, 2013. DOI
- 4.Delivering Precision Oncology in a Community Cancer Program: Results From a Prospective Observational Study — JCO Precision Oncology, 2018. DOI
- 5.Phase II Study of Dichloroacetate (DCA) in Combination with Chemoradiotherapy for Unresected, Locally Advanced Head and Neck Squamous Cell Carcinoma — Research Square, 2021. DOI
- 6.The difference between general anesthesia and peripheral nerve block in terms of postoperative functional recovery after orthopaedic upper limb surgery: Systematic review — Medical Science, 2025. DOI
- 7.Low Thyroid Function Leads to Cardiac Atrophy With Chamber Dilatation, Impaired Myocardial Blood Flow, Loss of Arterioles, and Severe Systolic Dysfunction — Circulation, 2005. DOI
- 8.Thyroid hormone activates Akt and prevents serum starvation-induced cell death in neonatal rat cardiomyocytes — Journal of Molecular and Cellular Cardiology, 2005. DOI
- 9.
- 10.Effects of Excessive Long-Term Exercise on Cardiac Function and Myocyte Remodeling in Hypertensive Heart Failure Rats — Hypertension, 2007. DOI
- 11.Treatment of subclinical hypothyroidism reverses ischemia and prevents myocyte loss and progressive LV dysfunction in hamsters with dilated cardiomyopathy — American Journal of Physiology-Heart and Circulatory Physiology, 2005. DOI
- 12.The Impact of State Firearm Laws on Homicide Rates in Suburban and Rural Areas Compared to Large Cities in the United States, 1991‐2016 — The Journal of Rural Health, 2019. DOI
- 13.A <scp>WIN</scp> Consortium phase I study exploring avelumab, palbociclib, and axitinib in advanced non‐small cell lung cancer — Cancer Medicine, 2022. DOI
- 14.
- 15.Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival — npj Precision Oncology, 2021. DOI
- 16.Real-World outcomes of Non-Small cell lung cancer patients harbouring KRAS G12C and KRAS G12D mutations — Lung Cancer, 2025. DOI
- 17.Atovaquone-Proguanil: A Promising Therapy for Persistent Relapsing Babesiosis — Case Reports in Infectious Diseases, 2024. DOI
- 18.Telemedicine Trends in Radiation Oncology at Two Large Multi-Specialty Cancer Centers from 2019 to 2023 — International Journal of Radiation Oncology*Biology*Physics, 2025. DOI
- 19.Always Best Connected (ABC) and Perceived Value: An Analytical Study — Otago University Research Archive (University of Otago), 2011.
- 20.
- 21.Pembrolizumab Induced Acute Kidney Injury and Liver Injury in a Patient with Malignant Melanoma. — PubMed, 2022.
- 22.Systemic mastocytosis masquerading as metastatic breast carcinoma. — PubMed, 2004.
- 23.Radiation Therapy Induced Esophageal Ulcer. — PubMed, 2018.
- 24.Abstract 5494: Cost analysis of genomic-directed therapy in patients with metastatic lung and colorectal cancers — Cancer Research, 2015. DOI
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