Research-informed health explainers
Plain-language guides to conditions, treatments, and medications — each one grounded in peer-reviewed research from the specialists in our directory.
65 articles · Page 1 of 6
Ablation vs Medication for AFib: Which Is Better?
Plain-language comparison of catheter ablation and antiarrhythmic medication for atrial fibrillation, grounded in the CABANA trial and landmark electrophysiology research.
Douglas Packer, M.D. · Hugh Calkins, M.D. · Edward Gerstenfeld, MD
Academic vs Community Cancer Care: Which Is Better?
Choosing between an academic cancer center and a community oncologist? What the research shows about when each setting produces better outcomes.
Julie Sosa, MD · Jennifer Temel, MD · Ramaswamy Govindan, MD · Al Benson, MD
Ankylosing Spondylitis vs Axial SpA: Treatment Differences
Plain-language comparison of ankylosing spondylitis vs axial spondyloarthritis treatment. Same drug classes, different diagnostic thresholds.
Lianne Gensler, M.D. · Alan Kivitz, MD · Arthur Kavanaugh, M.D. · Eric Ruderman, MD
Botox vs CGRP Injections for Migraines: Key Differences
Plain-language comparison of onabotulinumtoxinA (Botox) and CGRP monoclonal antibodies for chronic migraine prevention, with evidence from landmark trials.
Peter Goadsby, MD · Charles Argoff, MD · Richard Lipton, MD
Bupropion-Naltrexone vs Semaglutide for Weight Loss
Compare bupropion-naltrexone (Contrave) and semaglutide (Wegovy) for weight loss: efficacy data, side effects, cost, cardiovascular outcomes, and how to choose.
Caroline Apovian, M.D. · Ildiko Lingvay, MD · Jonathan Purnell, MD · Amy Rothberg, MD
Catheter Ablation vs Open-Heart Surgery for AFib
Plain-language comparison of catheter ablation and surgical maze for atrial fibrillation, grounded in peer-reviewed research from leading electrophysiologists.
Hugh Calkins, M.D. · Edward Gerstenfeld, MD · Douglas Packer, M.D.
CGRP Injections for Migraine: How Effective Are They Really?
A plain-language guide to CGRP monoclonal antibody injections for migraine prevention, grounded in the peer-reviewed research of leading headache specialists.
Peter Goadsby, MD · Stephen Silberstein, M.D. · Richard Lipton, MD
Chemo-Induced Peripheral Neuropathy: Treatment Options
Evidence-based guide to chemotherapy-induced peripheral neuropathy (CIPN) — what causes it, which chemotherapy agents are highest risk, what treatment options exist, and what recovery looks like.
Ahmet Hoke, M.D. · Michael Rowbotham, M.D. · Eva Feldman, MD
Chronic Daily Headache: Causes and How to Break the Cycle
Evidence-based explainer on the four types of chronic daily headache, the mechanisms that perpetuate them, and the treatment approaches most likely to work.
David Borsook, MD PHD · Richard Lipton, MD · Charles Argoff, MD
Chronic Pancreatitis vs Pancreatic Cancer: Pain Differences
Learn the key differences in pain patterns between chronic pancreatitis and pancreatic cancer — location, triggers, timing, and when to seek urgent evaluation.
Santhi Vege, M.D. · Tyler Stevens, M.D. · Vikesh Singh, M.D., M.S. · Michael Goggins, M.D.
CIDP vs Guillain-Barré Syndrome: Key Differences
Plain-language comparison of CIDP and GBS — two autoimmune demyelinating neuropathies — including how they are diagnosed and how treatment differs based on time course.
Thomas Brannagan, MD · Michael Rowbotham, M.D. · Eva Feldman, MD
Colonoscopy vs Cologuard: Which Screening Is Right for You?
Colonoscopy and Cologuard both screen for colorectal cancer, but they work differently and suit different patients. Here's what the evidence says about each.
Seth Sweetser, MD · Dayna Early, MD · Sameer Saini, M.D. · Juan Carlos Bucobo, M.D.