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Expert list · Last reviewed April 17, 2026

Top Ophthalmologists for Intravitreal Injections in Ohio

Ohio ophthalmologists with deep retinal research and clinical volume in intravitreal injections for macular degeneration, diabetic eye disease, and vein occlusion.

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Ohio has a tight cluster of ophthalmologists whose research and clinical volume in intravitreal injections place them among the most experienced in the country, and nearly all of them practice within the Cleveland Clinic system.

Intravitreal injections are in-office shots of medication into the back of the eye, most often used to treat wet age-related macular degeneration, diabetic macular edema, and retinal vein occlusion. The providers below are distinguished by a mix of pivotal trial participation, leadership roles at the Cole Eye Institute, and research on when and how to inject, image, and follow patients over years of care.

Peter Kaiser

Peter Kaiser, MD

Chaney Family Endowed Chair in Ophthalmology Research; Professor of Ophthalmology; Director, Centre for Ocular Research & Education (CORE)

Cleveland Clinic Cole Eye Institute

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Dr. Peter Kaiser holds an endowed chair in ophthalmology research at the Cleveland Clinic Cole Eye Institute and has been a principal investigator on many of the clinical trials that established current anti-VEGF injection regimens. His clinic focuses on wet macular degeneration, diabetic retinopathy, and vein occlusion — the three main reasons a patient needs regular injections. He co-led the international classification system for vitreomacular traction and macular hole 1, which retina specialists across the country still use to decide whether an eye needs injection, surgery, or simple observation.

Justis Ehlers

Justis Ehlers, M.D.

Norman C. and Donna L. Harbert Endowed Chair of Ophthalmic Research and Director of the Tony and Leona Campane Center for Excellence in Image-Guided Surgery and Advanced Imaging Research at the Cole Eye Institute

Cleveland Clinic

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Dr. Justis Ehlers directs the Campane Center for image-guided surgery at the Cole Eye Institute, where he sees patients with complex retinal disease and uveal melanoma. If you have a retinal vein occlusion and are being told you'll need injections for years rather than months, his work is a reason to ask your doctor about long-term monitoring plans 14. His lab also helped establish the gene expression patterns that now guide treatment for eye tumors 121516.

Andrew Schachat

Andrew Schachat, M.D.

Vice Chairman for Clinical Affairs and Director of Clinical Research, Retinal Diseases

South Pointe Hospital

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Dr. Andrew Schachat serves as Vice Chairman for Clinical Affairs and Director of Clinical Research for retinal diseases at Cleveland Clinic, with patient clinics at South Pointe Hospital in Beachwood. He has spent decades shaping how large retina practices run — which means how injection appointments are scheduled, how follow-up imaging is ordered, and how the practice tracks whether your vision is actually improving. Patients referred into the Cole Eye Institute for macular degeneration often end up in a workflow he helped design.

Dr. Elias Traboulsi is a Cleveland Clinic ophthalmologist whose research helped identify several of the genes that cause inherited retinal diseases 7811. He is the right starting point if your vision loss runs in your family or if a routine eye exam has turned up an unusual retinal finding that no one can quite explain. His team also contributed to the foundational work on gene therapy for RPE65-related blindness 9, the first FDA-approved gene therapy for an inherited eye condition.

Dr. William Dupps is a Cleveland Clinic corneal specialist whose engineering background shaped how ophthalmologists measure the mechanical health of the cornea 2. While his primary focus is cornea and refractive surgery rather than retinal injections, patients considering injection therapy often have overlapping corneal issues — past LASIK, dry eye, or keratoconus — and his research on corneal biomechanics 3 and imaging 4 informs how retina teams at the same institution screen patients before any eye procedure.

Dr. James Randleman is a Cleveland Clinic refractive surgeon best known for building the ectasia risk score, the standard screening tool used to decide whether a patient is safe for LASIK 1720. His work matters for injection patients too: older adults who had LASIK decades ago sometimes develop complications that affect how their retina specialist measures the eye and tracks response to treatment. Practices that use his framework tend to screen more carefully before and during injection courses.

What to look for in an ophthalmologist for intravitreal injections

  • Board certification in ophthalmology, with retina fellowship training if you need ongoing injections
  • Affiliation with a teaching hospital or dedicated eye institute
  • A clinic that handles high volumes of the specific condition you have (wet AMD, diabetic macular edema, vein occlusion)
  • Access to optical coherence tomography (OCT) imaging at every visit
  • Clear communication about wait times and whether they're accepting new patients
  • Acceptance of your insurance, including any step therapy rules the plan enforces

Questions to ask before your first appointment

  • How many patients with my condition do you treat each year?
  • Will I see the same doctor at every injection visit, or rotate through the practice?
  • Which medication will you start with, and why that one over the alternatives?
  • How will we know if the treatment is working, and when would we switch drugs?
  • What does a typical injection visit look like, and how long does it take?
  • What side effects should I call about the same day?

The bottom line

If you need intravitreal injections in Ohio, the Cleveland Clinic Cole Eye Institute concentrates more research depth and patient volume than anywhere else in the state. Start with a referral from your regular eye doctor or primary care physician, confirm the retina specialist is accepting new patients on your insurance, and bring a list of your past eye surgeries and medications to the first visit. If you live closer to Columbus or Cincinnati, ask whether a local retina practice can coordinate care with a Cleveland specialist for second opinions on complex cases.

Sources

  1. 1.
    The International Vitreomacular Traction Study Group Classification of Vitreomacular Adhesion, Traction, and Macular HoleOphthalmology, 2013. DOI
  2. 2.
    Biomechanics and wound healing in the corneaExperimental Eye Research, 2006. DOI
  3. 3.
    Biomechanics of corneal ectasia and biomechanical treatmentsJournal of Cataract & Refractive Surgery, 2014. DOI
  4. 4.
    Novel Pachymetric Parameters Based on Corneal Tomography for Diagnosing KeratoconusJournal of Refractive Surgery, 2011. DOI
  5. 5.
    Visual Acuity, Refractive Error, and Endothelial Cell Density Six Months After Descemet Stripping and Automated Endothelial Keratoplasty (DSAEK)Cornea, 2007. DOI
  6. 6.
    Stromal haze, myofibroblasts, and surface irregularity after PRKExperimental Eye Research, 2005. DOI
  7. 7.
    Human microphthalmia associated with mutations in the retinal homeobox gene CHX10Nature Genetics, 2000. DOI
  8. 8.
    Bietti Crystalline Corneoretinal Dystrophy Is Caused by Mutations in the Novel Gene CYP4V2The American Journal of Human Genetics, 2004. DOI
  9. 9.
    Identifying photoreceptors in blind eyes caused by <i>RPE65</i> mutations: Prerequisite for human gene therapy successProceedings of the National Academy of Sciences, 2005. DOI
  10. 10.
    Prevalence and Importance of Pigmented Ocular Fundus Lesions in Gardner's SyndromeNew England Journal of Medicine, 1987. DOI
  11. 11.
    Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degenerationProceedings of the National Academy of Sciences, 2002. DOI
  12. 12.
    Gene Expression Profiling in Uveal Melanoma Reveals Two Molecular Classes and Predicts Metastatic DeathCancer Research, 2004. DOI
  13. 13.
    Prospective Trial of a Blood Supply-Based Technique of Pancreaticojejunostomy: Effect on Anastomotic Failure in the Whipple Procedure1Journal of the American College of Surgeons, 2002. DOI
  14. 14.
    Retinal Vein Occlusion: Beyond the Acute EventSurvey of Ophthalmology, 2011. DOI
  15. 15.
    Functional Gene Expression Analysis Uncovers Phenotypic Switch in Aggressive Uveal MelanomasCancer Research, 2006. DOI
  16. 16.
    <i>DDEF1</i> Is Located in an Amplified Region of Chromosome 8q and Is Overexpressed in Uveal MelanomaClinical Cancer Research, 2005. DOI
  17. 17.
    Risk Assessment for Ectasia after Corneal Refractive SurgeryOphthalmology, 2007. DOI
  18. 18.
    Mathematical Model to Compare the Relative Tensile Strength of the Cornea After PRK, LASIK, and Small Incision Lenticule ExtractionJournal of Refractive Surgery, 2013. DOI
  19. 19.
    Depth-dependent Cohesive Tensile Strength in Human Donor Corneas: Implications for Refractive SurgeryJournal of Refractive Surgery, 2008. DOI
  20. 20.
    Validation of the Ectasia Risk Score System for Preoperative Laser In Situ Keratomileusis ScreeningAmerican Journal of Ophthalmology, 2008. DOI
  21. 21.
    Corneal Ectasia After Laser In Situ Keratomileusis in Patients Without Apparent Preoperative Risk FactorsCornea, 2006. DOI

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