

Hematology
Ruben Mesa, MD
Enterprise Senior Vice President of Atrium Health; President, Atrium Health Levine Cancer; Executive Director, Atrium Health Wake Forest Baptist Comprehensive Cancer Center; Vice Dean for Cancer Programs; Charles L. Spurr MD Professor of Internal Medicine, Wake Forest University School of Medicine
Dr. Ruben Anthony Mesa, MD, is a distinguished hematologist and medical oncologist renowned for his expertise in myeloproliferative neoplasms (MPNs), a group of chronic leukemias including polycythemia vera, essential thrombocythemia, and myelofibrosis. These conditions often present with debilitating symptoms, bone marrow dysfunction, progression to acute leukemia, and increased mortality risk. Throughout his career, Dr. Mesa has focused on advancing research, drug development, and symptom mana
30+
Years in Practice
Credentials
Board Certifications
- Hematology (ABIM)
- Internal Medicine (ABIM)
- Medical Oncology
Education & Training
- Mayo Clinic Alix School of Medicine — M.D., 1995
Peer Recognition
- Castle Connolly — Top Doctor
2012-2026 (15 years)
- Mayo Clinic — Career awards for MPN research
- University of Illinois Urbana-Champaign College of Liberal Arts and Sciences — Distinguished Alumnus
2024
Clinical Focus
Subspecialties
Conditions & Treatments
Practice Details
Hospital Affiliations
- Atrium Health Carolinas Medical Center
- Atrium Health Wake Forest Baptist Comprehensive Cancer Center
- Wake Forest Baptist Medical Center
Languages
English
Experience
30+ years in practice