Hematology

Matthew Shupe, D.O.

Hematologist-Oncologist

Clear Lake, SD

Dr. Matthew P. Shupe, D.O., is a board-certified hematologist-oncologist specializing in the treatment of solid tumors and hematologic malignancies, with particular involvement in clinical trials for breast cancer, lung cancer, and hematologic conditions. He serves adult patient populations, including those in civilian and military healthcare systems, emphasizing evidence-based therapies integrated with compassionate, patient-centered care. Over a decade of experience spans hands-on clinical pra

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Credentials

Board Certifications

Internal Medicine (ABIM)
Hematology (ABIM)
Medical Oncology (ABIM)

Education & Training

Medical School: A.T. Still University, Kirksville College of Osteopathic Medicine (D.O., 2009)
Residency: San Antonio Uniformed Services Health Education Consortium (Internal Medicine, 2012)
Fellowship: San Antonio Uniformed Services Health Education Consortium (Hematology/Oncology, 2016)
Undergraduate: Seattle Pacific University (B.A. in Biology, Pre-Professional Medicine emphasis)

Years in Practice

17+ years

Peer Recognition

Healthgrades — Healthgrades Honor Roll

Clinical Focus

Subspecialties

Hematology & Oncology

Conditions & Treatments

Hematologic MalignanciesLymphomaMultiple MyelomaStem Cell TransplantLeukemia

Insurance(s) Accepted

Please verify your coverage with the provider — plan participation can change.

Practice Details

Hospital Affiliations

Jefferson Community Health & Life
Great Plains Health
CHI Health St. Elizabeth
Beatrice Community Hospital & Health Center, Inc
Nebraska Medicine

Languages

English

Conditions Dr. Shupe treats

Insurance accepted

Frequently asked

Does Dr. Shupe accept Aetna insurance?

Matthew Shupe's public profile lists Aetna, Blue Cross Blue Shield, and Cigna plus 4 more health plans as accepted plans. Plan participation can change — confirm directly with the practice before your visit.

Where does Dr. Shupe practice?

Matthew Shupe practices in Clear Lake, SD with hospital affiliations including Jefferson Community Health & Life, Great Plains Health, and CHI Health St. Elizabeth.

What does Dr. Shupe specialize in?

Matthew Shupe is a board-certified hematology specialist with focus areas in Hematology & Oncology.

How long has Dr. Shupe been practicing?

Matthew Shupe has 17+ years of clinical experience in hematology.

What is Dr. Shupe's medical training?

Public profile training history includes: Medical School: A.T. Still University, Kirksville College of Osteopathic Medicine (D.O., 2009); Residency: San Antonio Uniformed Services Health Education Consortium (Internal Medicine, 2012); Fellowship: San Antonio Uniformed Services Health Education Consortium (Hematology/Oncology, 2016).